Which cell type is NOT typically found in the dermis?

Keratinocytes are primarily found in the epidermis, the outermost layer of the skin. Their main role is to produce keratin, a key structural protein that helps protect the underlying tissues from damage, dehydration, and pathogens. While keratinocytes play a crucial role in the overall function and health of the skin, they are not typically present in the dermis, which lies beneath the epidermis.

In contrast, the dermis consists of various other cell types, including fibroblasts, which produce collagen and elastin fibers essential for the skin's strength and elasticity; mast cells, which are involved in immune responses and inflammation; and macrophages, which are important for the immune defense and in removing dead cells and debris. Therefore, identifying keratinocytes as the cell type not typically found in the dermis highlights the distinct roles and locations of different skin cells within the integumentary system.